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Tuesday, December 7, 2010

The other side of Aspirin


Aspirin not only serves to reduce the pain of the head. Consumption of low-dose aspirin every day a person has been shown to reduce colon cancer risk. According to a recent study in Scotland, the risk reduction was 22 percent when taking painkillers regularly.
 Who is not familiar with aspirin or acetylsalicylic acid (asetosal). This one drug has been known since hundreds of years ago and often used as an analgesic (pain or minor aches), antipyretic (drug fever), and anti-inflammatory or inflammation. In addition to nutritious treat various symptoms and disease, the benefits of aspirin has also been growing along with the incessant research scientists. In fact, previous studies have found that large doses of aspirin may reduce risk of colon cancer.
But this study is the first to show evidence that lower doses of aspirin, which also can reduce the risk of other side effects such as gastrointestinal bleeding, may also be effective in preventing colon cancer. This was disclosed Eric Jacobs, a division of pharmacoepidemiology strategic director at the American Cancer Society was quoted as saying the page healthday.com.
In the study researchers from Scotland asked 2279 people with colon cancer and 2907 other people who are not suffering from colon cancer. They were asked to answer questions about diet and lifestyle choices that can affect the increased risk of cancer.
 Participants were also asked how often they ate low-dose aspirin (75 milligrams) and non-aspirin NSAIDs (anti-inflammatory drugs non-steroidal) such as naproxen (Aleve, Naprosyn, etc.) and ibuprofen (Advil, Motrin, and other etc.) on the year before cancer diagnosis or during the study.
Approximately 18.1 percent of participants without cancer reported taking aspirin more during that period, compared with 15.5 percent of those suffering from colon cancer.
 Participants who reported taking low-dose aspirin regularly for a year or more, about 22 percent decreased risk of colon cancer.
 This decline occurred more clinically significant effect on those who reported taking low-dose aspirin for more than five years. The percentage is about 30 percent less likely to develop cancer than their counterparts who did not consume painkillers that.
 Although the greatest risk reduction occurred in those who consume more than 525 milligrams of aspirin a week, the effects of these drugs has remained there for the lowest daily dose.
Studies in Scotland this latest case is one of the largest to date that specifically examine the effects of low dose aspirin and show evidence that the use of low-dose aspirin for five years or more can also reduce the risk of colon cancer.

However, previous studies about the relationship of low-dose aspirin use and colon cancer risk have had mixed results. Hence, the results of this study need to be confirmed. This study also reveals that taking NSAIDs regularly is associated with reduced risk of colon cancer, compared with those who do not take painkillers it.
Even so, the study notes, taking NSAIDs of any type occur before diagnosis does not increase survival time in patients with colon cancer or affect the risk of death of each individual case. Subjects and controls the process of this study have been aligned with the age, sex, and health habits such as smoking, alcohol, and fiber intake.
This finding is also very accurate because the results have been adjusted to a weight problem, body mass index, and other factors. Own research results have been published recently in the journal Gut.
 "Previous epidemiological studies showed high doses of aspirin (325 milligrams of aspirin daily or a standard adult dose) and types of other NSAIDs reduce the risk of colorectal cancer," said Dr Andrew Chan, an assistant professor of medicine at Harvard Medical School and an expert gastroenterologis at Massachusetts General Hospital.
While the new findings provide a glimmer of hope of a promising new, while now many Americans began to frequently take aspirin to prevent cardiovascular disease, further research is needed before saying with certainty that low-dose aspirin is also effective.
 Because this retrospective study, it does depend on the memories of people about the use of aspirin, which may not be accurate. The researchers also noted, it is unknown whether subjects with colon cancer continue taking NSAIDs after diagnosis, which was clearly to limit the conclusions drawn from the data presented on patient survival.
 Established in the literature based on previous studies and this study now clearly proven aspirin is effective in reducing the risk of colon cancer. What is less clear and still somewhat controversial is the matter of how many doses of aspirin use in order to prevent continued.
Because aspirin can have dangerous side effects, organizations like the American Cancer Society does not recommend taking aspirin to ward off colon cancer.
 The decision to take aspirin should be decided by doctors and based on the balance of benefits for the prevention of heart disease are also against the risk of side effects. Based on background information in this study, worldwide colon cancer ranks second as a cause of death than other types of cancer, which has killed nearly half a million people per year. Jacobs stressed that adults must continue to run a colon cancer screening.
Colon cancer screening test to detect early and treat colorectal polyps before they turn into malignant cancer. The American Cancer Society strongly recommends that all men and women aged 50 years or older should get a colon cancer screening tests. Source: http://lifestyle.okezone.com

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